A CLR error on a computer is a fatal error that can prevent your computer from starting correctly and prevent many applications from starting. One of the most common CLR errors is the “CLR error 80004005” that occurs on Windows systems during the boot process. This error usually occurs when multiple .NET Framework is installed on the system at the same time. Although there may be two or more .NET Framework running on a system at the same time, some have compatibility issues. To fix the CLR error, multiple platforms must be uninstalled and properly reinstalled.

Docker CLR error 80004005 occurs when multiple instances of the .NET Framework try to run an application. In addition, the CLR error often occurs with third-party applications that do not have sufficient permissions to run.

This can also happen if the program is not compatible with the Windows operating system, or if Windows is out of date and not updated to the latest version available. A corrupted .NET installation is also known to cause a CLR error.

Remove multiple instances and reinstall the .NET Framework

The most common CLR error is caused by multiple instances of the .NET Framework as described above. Although the error can usually be resolved by running the application as an administrator, sometimes it does not work. In this case, uninstalling and then reinstalling the .NET Framework will fix the problem.

Uninstall and then reinstall Microsoft .NET Framework to resolve an Autodesk software issue such as, for example, a “general error” during installation (due to conflict with installer requirements) or any type of malfunction or crash during normal work.

To uninstall Microsoft .NET Framework:

For older Windows operating systems:

Open Programs and Features in the Windows Control Panel (or add or remove programs for Windows XP). An easy way to find it on systems other than Windows XP is to type “programs and features” in the search box at the bottom of the Start menu.
Uninstall anything that starts with “Microsoft .NET” and run the latest versions first.

Note. “Microsoft .NET” is not listed in the list of installed programs on Windows 8, 8.1, and 10. If you read “View installed updates” under “Programs and Features on Windows 8 and 8.1”, you can find the corresponding KB number and uninstall it this way.

To reinstall Microsoft .NET Framework:

Download and install the latest .NET runtime:

If the latest updates from Microsoft are not installed on Windows 10, you can install the latest .NET Framework. Current updates include updates to the .NET Framework.

Note. The current version of .NET 4 includes all previous updates to version 4. .NET 3.5 SP1 includes 2.0 and 3.0. The first .NET 1.1 is no longer supported. This is only necessary for very old Windows systems and software.